Antoni van Leeuwenhoek Antoni was a Dutch maker of microscopes, who made discoveries concerning protozoa, red blood cells, capillary systems, and the life cycles of insects. He was born in Holland in 1632 and received little or no scientific education. While a haberdasher and a chamberlain for the sheriffs of Delft, he devised, as a hobby, his single, tiny, double-convex lenses mounted between brass plates and held close to the eye. Through them he was able to peer at objects mounted on pinheads, magnifying them up to 300 times. In 1668 he confirmed and developed the discovery by Italian anatomist Marcello Malpighi of capillary systems, demonstrating how the red corpuscles circulated through the capillaries of a rabbit's ear and The web of a frog's foot. In 1674 he gave the first accurate description of red blood corpuscles. He then observed what he called animalcule in pond water, rainwater, in human saliva, and in 1677 he described the spermatozoa of both insects and humans. He opposed the prevalent theory of spontaneous generation and demonstrated that granary weevils, fleas, and mussels are not created from wheat grains and sand but develop from tiny eggs. He described thelife cycle of ants, showing how the larvae and pupae originate from eggs.He also observed plant and muscle tissue, and described three types of bacteria: bacilli, cocci, and spirilla. He kept the craft of making his lenses a secret, however, so that not until the improvement of the compound microscope in the 19th century was the next observation of bacteria made.